Titre:
Smart electro-optic platforms for bio-photostimulation and biomarkers detection
Conférencier:
Benoit Gosselin ,
Université Laval
Lieu:
ZOOM / https://us02web.zoom.us/j/84448440549?pwd=djR4UGpPcnJxSnBMRWQ3dWROTnozUT0 ,
Date et heure:
mercredi le 19 octobre 2022 de
10:00 à 11:30
Résumé:
This talk will present the design of electro-optic microsystems enabling in-situ biomarker sensing in biological samples and in live animal models. We will present the design of different CMOS integrated circuits to perform photostimulation and electrophysiology recording, in parallel, within these implantable and ambulatory systems. We will cover the design of high-sensitivity custom integrated CMOS photosensors for photometry sensing under low illumination conditions. High-performance circuit solutions will be presented to increase photosensors dynamic range. We will present miniature spectrophotometers to perform diffuse multi-wavelength spectroscopy for detecting biomarkers in real time within micro-volume samples. Then, we will show new integrated circuit strategies to perform data analysis in the chip to avoid delays and latency, and to allow for closed-loop bio-stimulation/sensing strategies. Finally, we will present different experimental results obtained in-vivo after performing photo-stimulation and electrophysiology recording in parallels in live transgenic rodents using these systems.
Note biographique: Benoit Gosselin obtained the Ph.D. degree in Electrical Eng. from École Polytechnique de Montréal in 2009, and he was an NSERC Postdoctoral Fellow at the Georgia Institute of Technology in 2010. He is currently a Full Professor at the Depart. of ECE at Université Laval, where he holds the Canada Research Chair in Smart Biomedical Microsystems. His research interests include wireless microsystems for brain computer interfaces, analog/mixed-mode and RF integrated circuits for neural engineering, interface circuits of implantable sensors/actuators and point-of-care diagnostic microsystems for personalized healthcare. Dr Gosselin is an Associate Editor of the IEEE Transactions on Biomedical Circuits and Systems and he is Chair and Founder of the IEEE CAS/EMB Quebec Chapter (2015 Best New Chapter Award). He served on the committees of several int’l IEEE conferences including NEWCAS, EMBC, LSC and ISCAS. His significant contribution to biomedical microsystems research led to commercializing the first wireless electro-optic bioimplant to study the development of brain diseases in freely behaving animal models by Doric Lenses Inc. He is Fellow of the Canadian Academy of Engineering, and he has received several awards, including the prestigious NSERC Brockhouse Canada Prize, and the Prix Génie Innovation of the Quebec professional engineering association OIQ.